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Sareum Holdings Plc
Unit 2A
Langford Arch London Road,Pampisford
Phone: +44 1223497700p:+44 1223497700 CAMBRIDGE, CB22 3FX  United Kingdom Ticker: SARSAR
Business Summary
Sareum Holdings plc is a United Kingdom-based biotechnology company. The principal activity of the Company is the discovery and development of new therapeutic drugs using a combination of skills in biology, computational chemistry and medicinal chemistry. The Company's internal programs focus on distinct dual tyrosine kinase 2 (TYK2)/ Janus kinase 1 (JAK1) inhibitors, which are progressing through preclinical development as therapies for autoimmune diseases and cancers. Its lead candidate, SDC-1801, simultaneously inhibits TYK2 and JAK1. SDC-1801 is a potential treatment for a range of autoimmune diseases, with an initial focus on psoriasis. It is also developing SDC-1802, a TYK2/JAK1 inhibitor with a potential application for cancer immunotherapy. The Company also has an interest in SRA737, an orally bioavailable small molecule inhibitor of checkpoint kinase 1 (Chk1), a key regulator of important cell cycle checkpoints and a central mediator of the DNA damage response (DDR) network.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-----

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/20236/30/2023Yes----

Industries
SIC Code Description
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Non-Executive Chairman of the Board Stephen B.Parker 64 5/17/2016 5/17/2016
Chief Executive Officer, Founder, Executive Director Tim J.Mitchell
Founder, Chief Scientific Officer, Executive Director John C.Reader 55
Secretary, Non-Executive Director CliveBirch 69 1/1/2022 11/13/2018
Non-Executive Director Michael J.Owen 73 11/13/2018 11/13/2018

Business Names
Business Name
SAR
Sareum Holdings Plc

General Information
Number of Employees: 5 (As of 6/30/2023)
Outstanding Shares: 101,578,309 (As of 4/18/2024)
Stock Exchange: LON
Fax Number: +44 1223497701


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Saturday, April 27, 2024