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Amylyx Pharmaceuticals Inc
43 THORNDIKE STREET
Phone: (617) 682-0917p:617 682-0917 CAMBRIDGE, MA  02141  United States Ticker: AMLXAMLX
Business Summary
Amylyx Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company. The Company is focused on three investigational therapies across several neurodegenerative and endocrine diseases. Its lead investigational asset is avexitide, an investigational, first-in-class glucagon-like peptide-1 (GLP-1) receptor antagonist. Avexitide has been evaluated as a treatment for Post-Bariatric Hypoglycemia (PBH) and congenital HI, two indications characterized by hyperinsulinemic hypoglycemia. In addition to avexitide, it is advancing AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol in Wolfram syndrome and progressive supranuclear palsy (PSP), and AMX0114 in amyotrophic lateral sclerosis (ALS). AMX0035 is designed to mitigate neurodegeneration by targeting endoplasmic reticulum stress and mitochondrial dysfunction, two cellular processes central to neuronal cell death and neurodegeneration. AMX0114 is an investigational antisense oligonucleotide.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
-Yes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
12/31/202412/31/2024YesYes--Yes

Industries
SIC Code Description
2834 Pharmaceutical preparations
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Chair of the Board of Directors George M.Milne 80 12/1/2021 1/1/2015
Co-Chief Executive Officer, Director Joshua B.Cohen 32 1/1/2014 1/1/2014
Co-Chief Executive Officer, Director JustinKlee 33 1/1/2014 1/1/2014
8 additional Officers and Directors records available in full report.

Business Names
Business Name
AMLX
Amylyx Pharmaceuticals Canada Inc.
Amylyx Pharmaceuticals Distribution Ltd.
5 additional Business Names available in full report.

General Information
Number of Employees: 123 (As of 12/31/2024)
Outstanding Shares: 88,602,468 (As of 2/28/2025)
Shareholders: 17
Stock Exchange: NASD
Federal Tax Id: 464600503
Fax Number: (302) 636-5454


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Tuesday, April 8, 2025