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Applied Therapeutics Inc
545 5TH AVENUE, SUITE 1400
Phone: (212) 220-9226p:212 220-9226 NEW YORK, NY  10017  United States Ticker: APLTAPLT

Business Summary
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company engaged in the development of drug candidates against validated molecular targets in rare diseases. The Company’s lead drug candidate, govorestat, is a central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of CNS rare metabolic diseases, including classic galactosemia, sorbitol dehydrogenase (SORD) deficiency and phosphomannomutase 2 (PMM2)-congenital disorder glycosylation (CDG). The Company is also developing AT-001, an investigational, ARI developed as an oral therapy for the treatment of diabetic cardiomyopathy (DbCM). It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type II diabetes. The Company’s pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, and has demonstrated strong retinal penetrance, for the treatment of diabetic retinopathy (DR).

Scores and Ratings
FRISK®
Score
Z''
Score
PAYCE®
Score
DBT
Index
Moody's
Rating
Fitch
Rating
DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement
Last
Audit

News
SEC
Filings
Bankruptcy
Filings
Suit &
Judgment
Filings
Tax
Lien
Filings
3/31/202512/31/2024YesYes---

Officers and Directors

Title

Name

Age
Title
Date
Start
Date
Executive Chairman of the Board John H.Johnson 67 12/19/2024 12/19/2024
Interim Chief Executive Officer, Chief Financial Officer Leslie D.Funtleyder 55 12/1/2024 6/1/2016
Chief Operating Officer and Chief Business Officer ConstantineChinoporos 58 12/28/2023 12/28/2023
6 additional Officers and Directors records available in full report.

General Information
Number of Employees: 35 (As of 12/31/2024)
Outstanding Shares: 141,575,526 (As of 4/11/2025)
Shareholders: 30
Stock Exchange: NASD
Fax Number: (302) 636-5454


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Thursday, June 5, 2025